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KMID : 0338420190340020305
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Korean Journal of Internal Medicine
2019 Volume.34 No. 2 p.305 ~ p.314
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Clinical features of snoring patients during sedative endoscopy
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Chung Jung-Wha
Kim Na-Young
Wee Jee-Hye
Lee Jae-Bong
Lee Jong-Chan
Kwon Soo-Hoon
Hwang Young-Jae
Yoon Hyuk
Shin Cheol-Min
Park Young-Soo
Lee Dong-Ho
Kim Jin-Wook
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Abstract
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Background/Aims: Snoring is the sound of turbulence and vibration of the upper respiratory tissues and has been identified as a risk factor of obstructive sleep apnea (OSA) and cardiovascular disease. The aim of this study was to identify associated clinical factors in snoring patients undergoing sedative endoscopy.
Methods: A total of 49 patients who snored during standard sedative endoscopy and 127 controls were prospectively enrolled from June 2015 to June 2016. The Korean version of the Berlin Questionnaire was used to identify risk factors of OSA. Clinical information, including comorbidities, was collected from electronic medical records.
Results: The snoring group showed a higher risk of OSA (42.9% vs. 26.8%, p = 0.039), and a higher prevalence of coronary artery disease (10.2% vs. 0.8%, p = 0.007) and advanced gastric cancer (12.2% vs. 2.4%, p = 0.015) compared with the control group. Multivariate analysis showed that coronary artery disease (odds ratio [OR], 13.93; 95% confidence interval [CI], 1.24 to 155.90; p = 0.033) and advanced gastric cancer (OR, 5.21; 95% CI, 1.01 to 26.98; p = 0.049) were significantly associated with snoring. However, a history of gastrectomy showed only a marginally significant association with snoring (OR, 2.16; 95% CI, 0.91 to 5.11; p = 0.079).
Conclusions: Patients who snore during sedative endoscopy may need to be evaluated for possible coronary artery disease.
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KEYWORD
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Snoring, Stomach neoplasms, Coronary artery disease, Sleep apnea, obstructive, Surveys and questionnaires
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